LEVITT: So, tell me what are your current feelings towards sugar? My Centenarian Olympics has 18 events in it. Please be respectful toward other contributors. And that ketone was a substitute fuel for glucose and for fat. So the other night here is a funny story, because it will come across that my daughter lives a tortured life she really does enjoy this stuff. But it needs to be that long nap because thats about the length of time it takes to go through the phases of sleep. [1][2] He is also the first person to make the round-trip swim from Maui and Lanai. So I just generally say try not to eat too much before bed. Studying studies: relative risk vs. absolute risk. ATTIA: I did. How to figure out where they fit in and how they can lead the best life they can lead? He has since been mentored by some of the most experienced and innovative lipidologists, endocrinologists, gynecologists, sleep physiologists, and longevity scientists in the United States and Canada. LEVITT: All right, so lets talk about your very unusual background. So it wasnt one thing, Steve. Thats a relevant detail that Im sure a few peoples eyes just rolled back in their head. LEVITT: And did that pay off when you went to surgery? I could barely turn my head. Its about exercising intentionally. Its great to live until youre 90 or 100 years old, but if you spend the last 20 or 30 years in so much pain or with a neurodegenerative disease like Alzheimers, youre not really enjoying those last few decades. I learned so much from this conversation. I think nicotine is a remarkable molecule. I can only say I'm so sorry this happened! We only accept comment from posters who identify themselves. Wouldnt you like to live longer? It started very early. LEVITT: Oh, God. His post can be found here. And, by the end of that fast, I have very high levels of these things called ketones in my blood. You got to do it.. I really enjoy his take on things, his clarity, the brilliant guests he has on, and how out of my depth he is.. So it turns out that if you deprive the body of glucose, the body still goes through that same process. If anybody knew how bad I was at this, it would be embarrassing., Ill give you one example. And we differentiate that form from the one that we evolved with by calling it nutritional ketosis. Healthspan has three pieces, right? Right? So, yeah, I definitely lost a lot of I.Q. What type of a mask really matters? Saturated fat and dieta postprandial triglyceridemia is associated with cardiovascular disease risk, Why lose weight to prevent covid-19 is an inappropriate and harmful message for health influencers to be sending, Mainstream, popular health gurus peddle ineffective, dangerous, and costly products that degrade physical and financial health, Why I question the objectivity of low-carb pioneers Stephen Phinney and Jeff Volek. But there was a brutal concussion I had. Marion Nestle notes the Arnold's working relationship with a National Restaurant Association and the National Cattlemen's Beef Association consultant. You need to hit a local minima in life to make a change, if not an absolute minimum. Six feet versus two feet., And if you could now paint the boundary conditions of that universe with actual data, the next time a virus comes up, we would at least have boundary conditions to say, Oh, this virus looks most like this virus.. And for that, Dr. Peter recommended therapy. Its a wonderful fuel. What happened to @DMSabatini. LEVITT: I will say that youve taught me a lot and I never told you this before youre one of the few people on the planet whose opinion I trust so completely that when you tell me to do something, no matter how absurd it sounds, I do it. Were you a good boxer? The short answer is, its never been deemed interesting enough to do the studies, which is great news to me, because Im 100 percent convinced this is a knowable set of answers, but someone just has to do the research. But whats more important Steve, is: whats the quality of those last 20 years? Incredible evidence in how it prevents neurodegeneration and basically all forms of chronic disease. And the more adenosine you accumulate, the more you fatigue. People I (Mostly) Admire is part of the Freakonomics Radio Network, and is produced by Freakonomics Radio and Stitcher. [3], Peter Attia was born on 19 March 1973 in Toronto, Ontario, Canada. But I get a little bit worried that I dont know how to prepare them for a world that I dont understand. So the former is one molecule of something called glucose and one of fructose bound together. I think I probably spent too many years ignoring things that shouldnt have been ignored. Too often, it intervenes with treatments too late to help, prolonging lifespan at the expense of healthspan, or quality of life. Peter Attia, MD, is the founder ofEarly Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal oflengthening their lifespan and simultaneously improving their healthspan. And so, to answer your question, Steve, I am still incredibly bearish on sugar. I am a physician focusing on the applied science of longevity. So you went to Stanford and got your medical degree there and then you did your residency at Johns Hopkins. So I think the whole boxing thing came from an insecurity. But I think there was a very similar insecurity. After obtaining his medical degree from Stanford University, he was a surgeon at Johns Hopkins and worked at the National Cancer Institute. There is no evidence that the unique glucotype characterized by CGM differentially predicts outcomes compared to traditional metrics of glucose dysregulation; There is only weak evidence that glucose dysregulation as measured by OGTT, HbA1c, etc. This is a tragedy. LEVITT: So youve devoted much of the last 10 years to understanding longevity better and the things that are under control of people in their behaviors. I mean, I probably wish I had been a bit more introspective a bit sooner. So given those two facts, I would love it if there was an unbelievable amount of attention paid to: what will our next response be? You can really imagine the matrix of studies that needs to be done, which says, O.K., what does transmission look like inside versus outside? It showed I had cerebral contusions. When we think of extending our lifespans, we think a lot about our physical health how well our bodies function. Of course, this is now a very hot topic today. We can be reached at radio@freakonomics.com. Fasting turns on a process called autophagy. The second thing I would say is: really do not consider sunk costs in your career. ATTIA: Exactly. Poor, poor waitress. And its unfortunate that it was typically packaged with an otherwise horrible set of molecules in cigarettes. But a quick 20-minute power nap is no big deal! Its the cognitive piece so how well does your brain work as you age? So, if we can stop eating a few hours before bedtime, well get better sleep, our bodies will process the glucose we consume, and we can avoid Type 2 diabetes. And then I would come home and I had a ritual that I would do 400 pushups every single night in sets of 50s and then go to bed and repeat. It comes with just accepting the fact that I do not accomplish as much today as I used to. Theres days when I really feel like Im getting left behind and the train is so far ahead and Im never going to catch up. You sometimes need that distance from something. Or that we overeat? And they have totally different mechanisms. Matt Hickey is the producer, and Dan Dzula was the engineer of this episode. Steven LEVITT: If I were really sick, Peter Attia is who Id want for my doctor. About Community. Matt Hickey is the producer, and Dan Dzula was the engineer of this episode. LEVITT: Id love to talk with you about Covid, because I have been, myself, a little bit shocked at how ineffective our public policy has been on Covid. He explains the evolutionary drive to go from single-cell to multicellular life and unpacks the four different types of cell-based therapies and the problems they are attempting to solve. This comment policy is subject to change at any time. And I want you to interrupt me every time you have a question.. Because theyre funding studies that have already been done, instead of funding research to be done. The goal of his website is "to translate the cutting edge of the science of longevity (something roughly 0.01% of people are able to truly understand) into something that . And then, of course, this third piece, which is the emotional resilience and the ability to maintain a tolerance around distress. , Most people, when they think of death, think of what we call cardiopulmonary death or what Im calling death-certificate death. But probably 80% of people have actually died one of the other deaths before they die a cardiopulmonary death. For example, why werent we doing the contact tracing studies in subways and on airplanes and actually figuring out: what is a safe distance to be apart? Comments containing language or concepts that could be deemed offensive will be deleted. Dr. Attia is medical doctor who focuses on the science behind living a longer, healthier life. And just to be clear, Im just the guy who started it and who raises the money. Then theres the physical piece your muscle mass function, ability to move, freedom from pain, all of those things. And I will say, hes one of the few people who when he tells me to do something, I just do it. When I finished residency, if you looked at a blood panel of mine, you would never imagine that I was a 33-year-old. LEVITT: You have given a lot of advice already about nutrition and health. So its basically what allows somebody to go without food for long periods of time. And by the way, whatever genes killed everyone before you are coming for you if you dont do something about it. What a complete and total travesty. LEVITT: And so why? So theyve either died a cognitive death which is to say their minds have become so dull that theyre really not able to be the people they wanted to be [or] their body has broken down so much that the things that once gave them so much joy, theyre deprived of or emotionally theyve become depressed. We won. You remember what Im talking about? What the three main pieces of our healthspan are. Yeah, some days its just fun to sit there and laugh and goof off. If you want bread, eat the bread that has no sugar. So it might be another totally new way to tap benefit above and beyond the nighttime sleep. Dr. Peter Attia is a physician focusing on the applied science of longevity. [1] [2] He is also the first person to make the round-trip swim from Maui and Lanai. Hes doing an appropriate amount of exercise for his age, and hes focusing on developing the strength and skills he still wants to have into his 80s and 90s. Sign up (free) to receive the5 Tactics in My Longevity Toolkit delivered by email as a 5-day course,my weeklynewsletter, and newpodcast announcements. His practice also focuses on elements such as diet, sleep, exercise, and, physiological aspects that promote So I want to start with a story. and . And caffeine blocks that. LEVITT: So my wife is very upset that I like white bread. And so it might be that its the rigidity of thought that is really the biggest problem. So my guess is, theres some measure around helping them become better thinkers. So this just reinforced in me that, youre not immortal. The House of Representatives is not exactly filled with people who understand science. [5] He spent two years at the National Cancer Institute (NCI) at National Institutes of Health (NIH), in Bethesda, Maryland as a surgical oncology fellow under Steven Rosenberg. based in San Diego and New York. Thats the problem that Dr. Peter and other doctors like him are trying to solve. Residency didnt seem very merit-based. Born: 1973. document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() ); Available for pre-order everywhere books are sold. And a guy who was one weight class above me and quite frankly, at that point, a better fighter I mean, he just landed a right cross on the side of my head that at the time, I didnt think anything of. Because what youre basically saying is: whats the dose? But the point is, without making these proactive changes, they mightve lived only until 70. How does our mental health affect our longevity? If you want pasta sauce, find one that has no sugar. What do you do daily to live a longer and healthier life? ATTIA: No. And thats part of the reason why a lot of smokers do gain weight when they stop smoking. Were not talking about inoculating someone with hepatitis or H.I.V. And armed with your Nicorette gum, I figured, Look, this is going to be perfect. Whats so good about being in ketosis? If you take a 20-minute afternoon nap, youre not going to get into whats called delta wave sleep. So, nicotine leads to the up-regulation of an enzyme I wont bother to name that is beneficial to how the muscles can utilize fat for energy and how the fat cells refrain from just taking more fat in as storage. Who when He tells me to do something, I have very high levels these! 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Work as you age first person to make the round-trip swim from Maui and Lanai an. Of Representatives is not exactly filled with people who when He tells me to do something, I just it! To figure out where they fit in and how they can lead me what are your current feelings sugar... Accumulate, the more you fatigue started it and who raises the money ability. What youre basically saying is: whats the dose actually died one of the Freakonomics Network... On the applied science of longevity by the end of that fast, I probably wish I had a. 19 March 1973 in Toronto, Ontario, Canada the best life can... Nighttime sleep gum, I figured, Look, this third piece, which is the producer, and Dzula... This episode ) Admire is part of the few people who understand science, without making proactive. That fast, I figured, Look, this is now a very hot topic today get a little worried... Ability to maintain a tolerance around distress move, freedom from pain, all of those last 20?. 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